SYNTHESIS, COMPLETE ASSIGNMENT OF 1H- AND 13C-NMR SPECTRA AND ANTIOXIDANT ACTIVITY OF NEW AZINE DERIVATIVE BEARING COUMARIN MOIETY

Synthesis, complete assignment of 1H- and 13C-NMR spectra and antioxidant activity of new azine derivative bearing coumarin moiety

In this research, the synthesis of a new azine derivative with coumarin moiety was performed in three reaction steps, starting from 4-hydroxycoumarin.The first step in synthesis was the acetylation of 4-hydroxycoumarin to yield 3-acetyl-4-hydroxycoumarin and then the obtained 3-acetyl-4-hydroxycoumarin was reacted with hydrazine hydrate and give a

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Perspectives on advance research directives from individuals with mild cognitive impairment and family members: a qualitative interview study

BackgroundAdvance research directives (ARDs) provide a promising way to involve individuals with mild cognitive impairment (MCI) in research decisions before they lose the capacity to consent.At the same time, the views of people with MCI on ARDs are underexplored.This study assesses the perceptions of people with MCI and family members on the bene

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